BrainReference is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.
We aim to provide consumers with helpful, in-depth information about brain health products. Whether we make money or not on a certain page does not influence the core mission of our writers and medical reviewers, which is to publish content that is accurate and informative.
All product names, logos, and brands are the property of their respective owners.
For more information, see our full Advertising Disclosure
TwinLab DMAE Review – 8 Things To Look For
DMAE is a dietary supplement in the form of concentrated capsules containing DMAE or dimethylethanolamine. TwinLab was established in 1968, and entered the market with a liquid protein supplement. Later, the range of product expanded, and today the company markets over 1,000 products consisting of vitamins, minerals, herbs and teas.
DMAE is an organic compound used to treat a number of conditions affecting the central nervous system and the brain. Research has demonstrated that it works by increasing production of acetylcholine, a neurotransmitter which plays an important role in muscle activation, enhancement of sensory perceptions (when waking up) and sustaining attention.
It is mostly used as a memory and mood enhancer and is thought to improve intellectual functions. However, no clinical studies back-up its use for these purposes and its connection to choline and its role as a biochemical precursor to acetylcholine have been the subject of many disputes.
1) What is DMAE?
DMAE is the core ingredient in this formulation. Double-blind clinical trials have shown significant improvement of learning abilities for children diagnosed with attention deficit hyperactivity disorder (ADHD) or some other form of learning disability.
Due to the fact that DMAE may increase the levels of acetylcholine (though no there is no conclusive evidence), several studies have been conducted to determine its effect on people suffering from Alzheimer’s disease, Tardive Dyskinesia or Huntington’s Chorea. However, results were mixed and therefore inconclusive (some tests revealed it is no more effective than placebo).
2) Details on DMAE Ingredients and Uses
DMAE includes the following ingredients: DMAE, potato starch, gelatine, cellulose, magnesium stearate, medium chain triglycerides, and silica.
3) What Does DMAE Do?
There is very little information about this product posted online. According to the company, this formula is an effective memory enhancer.
Twinlab DMAE contains 2-Dimethylaminoethanol (DMAE), a common organic compound in many memory supplement formulas. Short-term clinical trials have shown an increase in alertness and vigilance with a positive influence on mood following administration of DMAE, minerals, and vitamins in patients suffering from borderline emotional disturbance.
Another study showed that this compound may be effective in treating the symptoms associated with ADHD (attention deficit hyperactivity disorder).
The recommended dose ofDMAE is 1 to 4 capsules per day. Users are urged to start out with a lower dose and then to increase it as they feel they need to but not to exceed the maximum.
Women who are pregnant or nursing and individuals who are taking prescription drugs are advised to talk with their doctor before taking DMAE.
4) DMAE Claims
- DMAE comes in the form of easy to assimilate capsules
- No added colours or coating, additives that can cause adverse reactions in people with allergies or on special diets
- Sufficient dose for a three month supply for a reasonable price (approximately $10 for a 100 capsules bottle)
5) Precautions of DMAE Use
- DMAE is not FDA approved
- Mixed results regarding the effectiveness of the active ingredient
- Mild side effects reported
6) DMAE Cost
Each bottle of Twinlab DMAE contains 100 capsules. Based on the maximum recommended dose of 4 capsules per day, one bottle should be enough for up to 25 days of treatment. The average price per capsule is what recommends Twinlab DMAE as an excellent purchase.
Twinlab DMAE orders can only be shipped within the 48 contiguous states in the USA. All orders that are more than $50 will be shipped for free. For orders less than $50 the cost will be calculated once the physical address is entered.
7) DMAE Directions
AsDMAE side effects, some consumers have been experiencing: drowsiness, elevated blood pressure, weight loss, insomnia. Some manufacturers warn against the use of DMAE by people with epilepsy or a history of convulsions. The recommended dose is one capsule daily as recommended by the healthcare professional.
8) Final Thoughts on DMAE
DMAE is marketed as a high quality highly concentrated formula containing the active ingredient called 2-Dimethylaminoethanol. Although the manufacturer does not specifically mention what are the ailment claims for their formula, DMAE is generally used as a memory and mood enhancer, treatment of ADHD and Alzheimer’s disease (with no conclusive results to support its use for these conditions).
It comes in the form of capsules, thus having the advantage of an easy swallowing and rapid dissolving, assuring a maximum effect in the shortest of time.
The manufacturer makes no warnings regarding interactions with other medications or the use of children and pregnant/nursing women.DMAE recommends patients to consult a healthcare professional when deciding to use this supplement.While DMAE may prove helpful, you should also consider a supplement to help you focus and improve attention.
Without a doubt, HCF® Happy, Calm & Focused is one of the top Amino Acids [Blend] supplements we've reviewed in years. HCF can offer a lot in terms of supporting focus, attention, clarity, and energy.
|DMAE Customers Also Purchased:||
10+ Yrs Proven
|HCF Happy, Calm & Focused
Customers Questions and Answers with DMAE
Twinlab DMAE includes the following ingredients: 2-Dimethylaminoethanol.
Twinlab DMAE is an amino-acid supplement advertised as a potent memory enhancer. The product contains high quality DMAE (2-Dimethylaminoethanol), which clinical trials have shown to increase alertness and vigilance with a positive influence on mood in patients suffering from borderline emotional disturbance. The recommended dose of Twinlab DMAE is 1 to 4 capsules per day. This supplement is offered by Twinlab.
There is little information about this particular product. While some research has been conducted to prove DMAE Effectiveness as a memory enhancer, the results are far from conclusive. On top of that, the complete lack of clinical evidence to support this formula is also concerning.
We always advise our readers to focus on supplements that have been fully researched and proven to work.
On the other hand, Twinlab DMAE is one of the cheapest DMAE-based formulas available at this moment. DMAE is safe to use the organic compound with very few reported side effects. Even without a free trial sample, buying and trying this product should be relatively risk-free.