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PS 100 Review – 8 Essential Things to Know
PS 100 is a dietary supplement based on the phospholipid with the same name, designed to promote brain function. The formula’s active ingredient, Phosphatidylserine, acts by increasing cellular communication, which supports the optimal fluidity of the neuronal membrane.
The product is formulated by Pure Encapsulations, which claims to manufacture hypo-allergenic supplements, free of artificial flavors or other preservatives that could interfere with the effectiveness of their products. The company has several products involved in clinical trials.
This formula is advertised as containing a standardized extract of Phosphatidylserine, supporting mental performance, cognition, and mental acuity (alertness, reaction time).
According to the manufacturer, PS 100 contains 95%-98% of soya-based Phosphatidylserine, the highest concentration. The manufacturer offers some information regarding clinical test results, which reveal the benefits of Phosphatidylserine on memory and cognition.

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1) PS 100 Quick Facts
Phosphatidylserine is a phospholipid found in all cell membranes. Although inconclusive, research has revealed beneficial effects on reducing the risk of dementia and cognitive decline. However, studies are in their preliminary stages and, therefore, limited. The Phosphatidylserine initially used was extracted from the bovine brain. Still, due to the danger of disease transmission, a soybeans based extract is now used.
This product also contains hypo-allergenic plant fiber derived from pine cellulose as it is a vegetarian product. Although the manufacturer lists no side effects, the formula is not recommended for pregnant and/or lactating women without a physician’s consent.
Furthermore, side effects such as insomnia and stomach upset have been reported for doses over 300mg of Phosphatidylserine based supplements. No unwanted effects have been identified from the formula’s interaction with other medications.
2) PS 100 Ingredients
PS 100 contains the following ingredient: Phosphatidylserine 100 mg.
3) Does PS 100 Work and it is Safe?
This formula is based on just one active ingredient: Phosphatidylserine or PS.
Phosphatidylserine is naturally produced in the body, but relevant intakes are mostly obtained through diet sources. This ingredient is most commonly derived from cabbage and soy. It is present in the membrane of every cell in the human body. PS concentration is increased in brain cells.
Phosphatidylserine is used to affect brain health, supporting cognitive function, emotional well-being, and behavior. A double-blind study that provided a daily supplementation of Phosphatidylserine for six months has shown an increase in cerebral metabolism and cognitive function. Another research has shown that users taking Phosphatidylserine have scored better in memory tests than the placebo drug users. Some studies showed this ingredient to be effective in reducing the risk of dementia in the elderly.
Still, future research has to be made to assess this claim. Over the past years, healthcare practitioners have prescribed this chemical for conditions such as Alzheimer’s disease, age-related mental decline, depression, and attention deficit-hyperactivity disorder. With doses of 300 mg, this ingredient comes with some side effects like insomnia and stomach upset.
The manufacturer suggests using three capsules per day, in divided dosage, with meals.
There are online testimonials about PS 100. What is being said includes:
- Dr. recommended this to lower cortisol, and has done the trick;
- Seems to be helping me with mental fogginess and mood.
4) PS 100 Claims
- Vegetarian formula;
- Hypo-allergenic;
- Reputable manufacturer;
- Good reviews from consumers.
5) Precautions of PS 100 Use
- Relatively high price – approximately $58 for a 20 day supply (full adult dosage);
- Inconclusive evidence of the effectiveness of the product.
6) PS 100 Price
This product can be purchased in two size containers, one that holds 60 capsules and the other that has 120, both come at a relatively high price. The small size container provides a 20-day supply at the suggested use of three capsules each day.
In contrast, the large container provides a 40 day supply. The manufacturer’s website does not offer the option of direct purchase. Still, this formula can be purchased from a range of physical and online retailers, some of which provide free delivery. There are no mentions of a free trial or money-back guarantee that are associated with this formula.
7) PS 100 Directions
The recommendations of use are three capsules per day, with meals, taken as individual doses.
8) Conclusion
The active ingredient, Phosphatidylserine, has been involved in various clinical trials, with positive results on cognitive, behavioral, and memory-related parameters. In terms of the benefits of reducing the risk of dementia in elders, the results have been classified by the FDA as inconclusive.
However, PS 100 has obtained good reviews from consumers regarding its effectiveness in improving memory, boosting energy, reducing cortisol levels, mental fogginess, and enhancing mood.
The formula is not FDA approved, as in the case of most nutritional supplements. A healthcare professional should be informed before using such a product.
Creating a healthy life means making lifestyle changes including a diet or supplementation that promotes optimal brain health.
When it comes to Fatty Acids [Blend] products, HCF® Happy, Calm & Focused is One of the most praised supplements we've reviewed in years. Its unique FQ formulation can offer a lot in terms of supporting cognitive health and general well-being.
Not to mention, we love that they offer ALL BrainReference access to a free sample for a limited time.
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PS 100 - Frequently Asked Questions
- Recent:
PS 100 includes Phosphatidylserine 100 mg, Hypo-Allergenic Plant Fiber, and vegetable cellulose (capsule).
PS 100 is a dietary supplement claimed to support specific brain function and promote overall brain health. The manufacturer is called Pure Encapsulations and is a United States company.
This formula is based on a single active ingredient, which also gives the name of this product. Phosphatidylserine is a naturally occurring chemical found in all body cells, but particularly in higher concentrations in brain cells. This formula may promote better memory, attention, and focus; while also potentially being effective with depression, Alzheimer's disease, and attention deficit-hyperactivity disorder.
PS 100 is a dietary supplement advertised as having brain health-enhancing therapeutic effects. Several similar products are available on the nutritional supplements market, some of which are in different price ranges. Therefore minimum research could prove useful.
There have been found several customer testimonials, none of which detailing the effects of long-term use. The active ingredient is a natural constituent of cells, and this formula supplements the amount the body can produce.
The manufacturer did not use any sugars, artificial colors, or flavors in this formula's blending process, making this an excellent choice for those seeking a natural brain boosting formula.
I used to have moments in a day in which I could not focus my attention on anything, this nearly cost me my job so I decided to find a solution. My brother suggested I should use this formula and it works wonders.
Before using this formula I used to be a fan of herbal supplements, but this one convinced me that there are no rules in regard of dietary supplements. The thing that caught my attention is that the active ingredient is naturally found in the body. This formula really helped me with my focus and I now have a better memory as well.