BrainReference is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.
We aim to provide consumers with helpful, in-depth information about brain health products. Whether we make money or not on a certain page does not influence the core mission of our writers and medical reviewers, which is to publish content that is accurate and informative.
All product names, logos, and brands are the property of their respective owners.
For more information, see our full Advertising Disclosure
Kavinace is an amino acid compound meant to supplement brain nutrition by promoting GABA levels, thus favoring a calming effect. It is produced by NeuroScience, a company specializing in research regarding the human’s body proper functioning, particularly the nervous, endocrine and immune systems.
NeuroScience a US-based company founded in 1999 that puts a strong focus on providing quality products in order to improve the life of their patients. They are the leading company in the Neuro-Endo-Immune Solutions industry, offering a large range of quality products, from sedatives and endocrine regulators to immunity boosters and gastrointestinal supplements.
Advertised as NeuroScience’s most calming product, Kavinace is designed as a GABAA and GABAB receptor enhancer that can easily cross the brain-blood barrier, providing fast and certified effects.
Kavinace contains: Vitamin B6 (as pyridoxine HCl & pyridoxal 5′-phosphate), Proprietary Blend: Taurine and 4-amino-3-phenylbutyric acid, Microcrystalline Cellulose, Vegetable Cellulose, Magnesium Stearate.
Kavinace works by stimulating the reception of GABA in the human brain, as well as through supplementing the amount of GABA already existent.
GABA is an amino-acid with the role of regulating the excitability of neurons in the human nervous system. In other words, it has a major role in how information is transmitted inside the brain and is essential for the proper functioning of the human body. Normally this substance is synthesized in the brain, although there is a large number of supplements, such as Kavinace, that claim that they can boost GABA levels by crossing the brain-blood barrier. It is unsure how much base can be put in this statement, seeing as GABA is scientifically proven to only cross said barrier in small amounts.
The major issue when taking GABA supplements is the possibility of mild withdrawal: when consuming these products you temporarily supplement the GABA levels in your brain, thus improving neurotransmission for a limited amount of time and lowering the body’s own production of the amino-acid. However, when the effects wear off your organism has to replace the missing production of GABA, which may result in temporary negative effects.
The recommended dose is 1-2 tablets once or twice daily. The product website claims that this is the optimal amount in order to reduce anxiety and promote sleep. It is also stated that Kevinace may help people suffering from elevated PEA and glutamate levels, as well as elevated epinephrine and norepinephrine. No side effects are mentioned.
- Kavinace contains no artificial flavors or colors.
- Product claims have been tested and proven.
- Scientifically proven effects of active ingredient.
- GABA supplements may present risk of withdrawal.
- Producer’s website only supplies to attested physicians.
- Expensive product: around 40$ for a 60 capsule bottle (which would last for approximately 2 weeks)
Kavinace is an amino-acid based product that promotes sleep, reduces anxiety and improves the general functioning of the brain. This statement is supported by medical and manufacturer research, as well as a wide selection of testimonials. There is, however, the running risk of permanently reducing the body’s own production of GABA if consuming this supplement in large doses or for extended periods of time. It would, thus, be recommended that people interested in this type of product to research alternatives, such as herbal-based products, before deciding whether to make a purchase.
One of the Amino Acids [Blend] supplements we’ve come to trust the most is HCF® Happy, Calm & Focused based on a unique FQ formula [15+ pure & effective associated neuro-nutrients] which research shows the ingredients may support memory, focus, attention, mood, and energy. People are reporting excellent results based on customer reviews we’ve seen and there is no mention of harmful side effects.
|Kavinace Customers Also Purchased:||
10+ Yrs Proven
|HCF Happy, Calm & Focused Featured
Manufactured by NeuroScience and widely available online, Kavinace is advertised as an effective solution for people suffering from insomnia and anxiety. According to the manufacturer, their formula increases GABA levels in the body, which will reduce the incidence of anxiety and sleeplessness.
The formula consists of a proprietary blend of 4-amino-3-phenylbutyric acid, 5-hydroxytryptophan (from Griffonia simplicifolia seed extract) and melatonin. Sadly, these key ingredients are not explained in detail and there are no clinical test results available to the public.
NeuroScience is a reputable company with a good track record in the past years, and because of that we expected more information from them regarding Kavinace. For instance, it is not very clear whether this supplement is more suitable as a treatment for mild forms of anxiety or insomnia or if it will help patients who suffer from severe forms of both.
Kavinace is an amino acid approach to brain nutrition supplementation designed to assist with sleep problems, anxiousness, and stress. The description of this supplement states that it can deliver the advertised benefits by supporting optimum GABA levels, the chief inhibitory neurotransmitter. The formula offered by NeuroScience contains a derivative of this naturally occurring neurotransmitter, known as Phenibut, which can easily cross the blood-brain barrier to producing the necessary effects.
Is Kavinace Right For You?
Kavinace is advertised as a powerful amino acid approach to brain nutrition supplementation. This brain supplement is claimed to be effective in promoting restful sleep and in reducing stress and anxiousness by supporting proper GABA levels. The company behind this product is NeuroScience.
According to their official website, this manufacturer is specialized in neurotransmitter clinical research and the development of medical programs for some of the today’s most challenging health conditions. The company’s product portfolio features several claimed “best sellers” such as TravaCor, AdreCor, Calm-PRT, Kavinace, Serene, LoraQuil, and GabaMax.
We were unable to find a dedicated website for the manufacturer, which, in an era where online presence is essential for any business, can be regarded as a shortcoming. Nonetheless, the reputation of this manufacturer and its good practices are a direct consequence of the positive image its many premium formulations hold among consumers.
NeuroScience claims this product is one of their “best calming supplements.” But the official statement goes beyond that and advertises Kavinace as a “uniquely designed to enhance GABAA and GABAB receptor function,” as well as promote healthy GABA levels.
According to the company, this formulation is different from traditional GABA supplementation. However, no arguments are offered to support this claim.
Ingredients of Kavinace
Kavinace includes the following ingredients: Proprietary Blend (Taurine and 4-amino-3-phenylbutyric acid), microcrystalline cellulose, vegetable cellulose, and magnesium stearate.
Effectiveness of Kavinace
If you have read other reviews on our website, then you will have seen our views regarding the inclusion of GABA in brain supplements. To quickly restate the problem of GABA, we want to point out that GABA does work, and is naturally produced by your brain, but artificially ingesting it only operates on the short time and fails to provide the over-advertised long term effects.
Artificial GABA can pass through the brain blood barrier and then affect your neurotransmitters, but as it is not a natural process, the effect will wear off, at which time your brain will need to build up its levels of natural GABA. To do this, many people need to take another supplement called L-Glutamine.
As such, we would agree that the supplement will calm people down, and reduce their anxiety; however, we disagree with the process used, as there is a much more natural way to reach the same state of feeling and well being.
In addition to taurine and 4-amino-3-phenylbutyric acid (commonly known as Phenibut), NeuroScience added one extra ingredient to this formula: Vitamin B6. This vitamin was added, probably, due to its property in assisting in GABA synthesis. It is important to note that Kaviance contains 5 milligrams of Vitamin B6, which is more than double the RDA of the vitamin
It is important for our readers to realize that GABA levels can be build up naturally, without assistance from various brain supplements. Artificial GABA is beneficial, but as a short-term solution only. Natural GABA can make you feel much calmer and be healthier by offering your brain the nourishment that it needs. This is done by ingesting the right neuro-nutrients and amino acids. You can find these in the ingredients of wholesome foods, but they are also found in an excellent amino acid supplement.
Kavinace is available in bottles of 60 or 120 vanilla-flavored chewable capsules. The recommended dosage is two capsules per day. Unfortunately, the Kavinace price is higher than the price for many other similar supplements, in part because of the brand under which it is manufactured.
NeuroScience does not have an official website to sell their products from. All NeuroScience supplements, Kaviance included, are available for purchase from various online retailers.
Does Kavinace Work?
If you are going to use an amino acid based supplement, then we would suggest something that does not contain artificial GABA. Don’t get us wrong. Artificial GABA might be beneficial as well, but only as a short-term solution.
While Kavinace brain supplement may be much better than many other brain supplements that we have reviewed here, we rated it down due to the artificial GABA content. On top of that, our research team was unable to find a satisfactory number of reviews or testimonials from real customers, which we consider to be another downside for this product.