BrainReference is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.
We aim to provide consumers with helpful, in-depth information about brain health products. Whether we make money or not on a certain page does not influence the core mission of our writers and medical reviewers, which is to publish content that is accurate and informative.
All product names, logos, and brands are the property of their respective owners.
For more information, see our full Advertising Disclosure
Jarrow Formulas 5-HTP Review – 5 Things You Need to Know
5-HTP (5-Hydroxytryptophan) is a popular, natural mood-enhancing supplement. Developed by Jarrow Formulas, the dietary supplement is marketed as an efficient way to deal with depression, anxiety, insomnia.
Jarrow Formulas, based in Los Angeles, California, is a formulator and supplier of superior nutritional supplements for more than 30 years and enjoys a solid reputation world-wide. Jarrow Formulas’ complete line of products include vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products. For example, the line of Acetyl-L-Carnitine supplements is developed for cardiovascular health. Jarro-Dophilus capsules address gastrointestinal problems. For brain and memory support, the company has formulated a variety of supplements and vegetables capsules (Ginkgo Biloba, Krill Oil, Mellow Tonin and many other products).
According to Jarrow Formulas official website, the company’s staff is professionally trained, has wide experience in scientific research and nutrition, and is involved in clinical studies and in working with researches from universities, institutes and other academic environments around the world.
5-HTP (5-Hydroxytryptophan) is an extract of Griffonia Simplicifolia seeds, a plant found on the coastal West Africa, and is marketed as a nutritional aid for depression and insomnia.
The company claims that the 5-HTP supplement “may be useful in promoting mental health, as a precursor to serotonin, and, as a melatonin precursor, may promote sleep.” Purity is assured by HPLC (high-performance liquid chromatography).
1) What is 5-HTP?
Product features5-HTP (5-Hydroxytryptophan) is a natural extract from Griffonia Simplicifolia seeds. The extract is a direct precursor of serotonin and is important for the production of melatonin, a hormone secreted by the pineal gland that aids biorhythm regulation.
There are no reports of clinical tests on Jarrow Formulas’ website. The interested consumer can find a documented overview of 5-HTP on the website of University of Maryland Medical Center, Complementary and Alternative Medicine Guide. According to the article, “5-HTP may help treat a wide variety of conditions related to low serotonin levels, including depression, fibromyalgia, insomnia, migraines and other headaches, obesity … preliminary tests indicate that 5-HTP may work as well as certain antidepressant drugs to treat people with mild-to-moderate depression.”
In relation to insomnia, the same article makes the statement that, “In one study, people who took 5-HTP went to sleep quicker and slept more deeply than those who took a placebo.”
According to the same article, side effects of 5-HTP are generally mild and may include nausea, heartburn, gas.
Suggested usage from Jarrow Formulas’ website: 1 capsule per day on an empty stomach or as directed by a qualified health care professional.
If you have a medical condition, are pregnant, lactating, trying to conceive, under the age of 18, or taking medication (especially SSRIs, MAOs, or sedatives) consult with your health care provider before using this product.
Testimonials are mostly positive. Consumers prone to anxiety attacks claim that the product helps them overcome the attack, and those who suffered from depression consider the product helpful to boost the mood (“a good mellow type of relaxing” wrote one consumer). Positive effect has been mentioned in relation to insomnia. Side-effects are few (nausea was mentioned and an excess of serotonin if the dosage exceeded the recommended dose).
2) 5-HTP Ingredients
Ingredients of 5-HTP
Active ingredient: 5-Hydroxytryptophan extract.
Other ingredients: Cellulose, magnesium stearate (vegetable source) and silicon dioxide.
The product does not contain wheat, gluten, soybean, dairy, egg, fish/shellfish, peanuts/tree nuts.
3) 5-HTP Health Benefits
- Jarrow Formulas is a reputable supplier of nutritional supplements, for more than 30 years, that enlisted a panel of professionally trained researchers.
- Jarrow Formulas claims that it closely monitors FDA and FTC regulations to ensure consumer safety and regulatory compliance of products.
- The product has been tested on humans with relative success and clinical studies have been mentioned on the website of the University of Maryland Medical Center.
- Positive testimonials.
- Affordable price, discounts and promotions offered by retailers and free shipping for orders over $20.
- Main active ingredient is a natural extract.
4) 5-HTP Product Warnings
- Jarrow Formulas does not provide reports of clinical studies.
- The company’s statements about the product have not been evaluated by the Food and Drug Administration.
- The consumer should be cautious before increasing the recommended dose.
- The product cannot be purchased from the company’s website.
- No trial samples.
- There are no customer reviews on the company’s website.
- Some retailers have shipping restrictions outside the USA. Consumers outside USA should check shipping availability before ordering
5) The Bottom Line – “Does it Work?”
5-HTP aids consumers who suffer from mild-to-moderate depression, anxiety attacks and insomnia. Studies made on this product showed positive results compared with other anti-depressants on the market.
Positive testimonials are encouraging, however if you take other anti-depressants, you should consult a doctor to avoid possible interactions.
The product should not be given to children.Looking to bring calm back while improving your overall health? Consider a product created specifically for promoting calm and overall brain health.
One of the Amino Acids [Blend] products we've come to trust the most is HCF® Happy, Calm & Focused. HCF provides users with a novel FQ formula [15+ pure & potent associated neuro-nutrients], which research shows the ingredients support mood, attention, energy, and focus. Users are describing outstanding results based on customer reviews we've seen, and there is no mention of adverse side effects.
|5-HTP Customers Also Bought:||
10+ Yrs Proven
|HCF Happy, Calm & Focused
5-HTP Questions & Answers
5-HTP is a dietary supplement developed by Jarrow Formulas, a reputed supplier of nutritional supplements for more than 30 years, based in Los Angeles, California. The active ingredient of 5-HTP is an extract of Griffonia Simplicifolia seeds, a plant that grows on the coastal West Africa. The product is marketed by the Jarrow Formulas as an efficient aid to deal with depression, anxiety and insomnia, and a natural mood-enhancing.
Jarrow Formulas does not offer clinical studies yet a more complex overview of the product is found on the website of University of Maryland Medical Center. The product can be purchased at an affordable price from retailers that offer promotions and discounts. Consumers from outside USA should consult with the retailer first as there are some shipping restrictions.