BrainReference is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.
We aim to provide consumers with helpful, in-depth information about brain health products. Whether we make money or not on a certain page does not influence the core mission of our writers and medical reviewers, which is to publish content that is accurate and informative.
All product names, logos, and brands are the property of their respective owners.
For more information, see our full Advertising Disclosure
Fungi Perfecti Lion’s Mane Review – 8 Things To Consider
Lion’s Mane is a dietary supplement designed to promote a healthy cognitive function by supporting memory and nerve function. The manufacturer of this formula is Fungi Perfecti, a company with 30 years of experience in producing various mushroom based products. The company does not only manufacture dietary supplements but offers a various range of mushroom based products including dietary foods, books, skin care products, seeds, and mushroom kits.
Lion’s Mane is included in the Hot Defense line of nutritional supplements and mushroom extracts along with numerous other products designed to assist with different health issues (antioxidant support, energy, healthy blood sugar levels or immune support, and many others). The formulation is advertised as a certified organic product based on US grown mushrooms. The active ingredient is the medicinal mushroom known as Lion’s Main, a traditional Chinese remedy against various conditions (digestive and immune problems, cancerous tumors, etc.). This mushroom has also been shown to improve mental capacities and performance through specific mechanisms that make it an effective treatment in memory related conditions. One vegetarian capsule contains 500 mg of freeze-dried Lion’s Mane mycelium.
Other details about Lion’s Mane (age limit, potential negative effects or warnings regarding combination with other drugs) are not provided by the producer.
1) What is Lion’s Mane?
Lion’s Mane is based on the therapeutic effects of a traditional medicinal mushroom known as Lion’s Mane. The plant is also known under the names Bearded Tooth Mushroom, Bearded Hedgehog Mushroom, or Bearded Tooth Fungus and is also edible (particularly used as an ingredient in Chinese vegetarian cuisine). Medicinally, the mushroom is believed to have potent antioxidant benefits making it a suitable natural treatment of elevated blood sugar levels and cholesterol. Current research showed certain cognitive benefits of the supplement including in the treatment of dementia, mild memory impairment and stimulation of nerve cell functioning and regeneration.
The most important compounds for the nervous system health are Hericenones and Erinacines, both chemicals believed to act as potent Nerve Growth Factors (NFGs). NFGs are molecules that play crucial functions in the differentiation (growth) and regeneration of neurons. However, the number of studies involving this mushroom as a neuro-protective agent is not very large, and some of these involve animal subjects. So far, the results have been positive and support the benefits of the active substances in preventing and reducing symptoms of neuro-degenerative conditions.
Lion’s Mane reviews are generally positive and support the effectiveness of this product in relieving leg cramps, reducing the frequency of seizure-like episodes after stroke, and improving brain function (including photographic memory, recall, and creativity).
The side effects of this supplement are not mentioned by the manufacturer, but there is a concern of increased allergic reactions occurrence. People with known allergies should be very careful if deciding to use such a formula.
2) Lion’s Mane Ingredients
Lion’s Mane contains the following ingredients: Lion’s Mane (Hericium erinaceus), freeze-dried myceliated brown rice, and Pullulan (an extra-cellular polysaccharide).
3) Does Lion’s Mane Work?
Lion’s Mane is a medicinal mushroom used traditionally in Chinese medicine mainly to treat stomach disorders (such as ulcers). Extracts from this plant have also been recommended for boosting the immune function, reduce inflammation and regulate cholesterol and blood sugar levels. More recent research indicates that this mushroom may also have important antioxidant and other neuroprotective effects that make it suitable for the treatment of conditions like Alzheimer’s disease, Parkinson’s disease, anxiety, and depression.
Lion’s Mane extracts have been shown to reduce mild cognitive impairment in 30 patients involved in a clinical trial that was conducted in 2009. Studies on animals showed a reduced amyloid beta buildup in the brains of mice (known to be one of the leading causes of Alzheimer’s disease). The brain benefits of this mushroom have been attributed to a class of compounds abundant in this plant, called Erinacines. Several types of Erinacines have been identified. These constituents have the ability to stimulate the activity of Nerve Growth Factor (NGF) synthesis, a protein considered essential for the growth, maintenance and proper function of neurons.
However, available research is not a sound basis for a viable hypothesis regarding its full spectrum of benefits and risks involved. People who suffer from chronic conditions should avoid using such treatment, without the prior consent of a specialized healthcare practitioner. Individuals who are allergic should also take special precautions because these supplements may worsen allergy symptoms.
There are testimonials posted online about Lion’s Mane. What is being stated include:
My work involves some very long hours of intense mental concentration. I feel this product has given me a lot of mental stamina and clarity for more extended periods of time/ I have seen so many improvements from this wonderful mushroom!!/ I started using this Lion’s Mane earlier this year for the lingering neurological issues, and I can tell a definite improvement. It didn’t happen overnight, but I did feel the effects after a month or so
The suggested dose is two capsules once per day, with or without food.
4) Lion’s Mane Benefits & Results
- The product is Certified Organic and is processed using a technology that helps preserve the qualities of the active substances without reducing their potency
- The formula benefits of a relatively high number of positive reviews in terms of effectiveness
- The manufacturer of this supplement is an experienced company (over 30 years of experience).
5) Precautions of Lion’s Mane Use
- The return policy is very restrictive and involves certain costs for the consumer
- The price listed on the official page is relatively high (the formula is much cheaper if ordered from other online retailers)
- The formula does not come with a money-back guarantee
- Shipping charges are not disclosed by the manufacturer (only after the client gives its personal information and e-mail address he will be given the information about shipping methods and costs)
6) Lion’s Mane Price
Lion’s Mane is packed in bottles of 60 capsules, which is the necessary monthly dose. While the product comes at a standard price which is relatively high (listed on the official site), the formula is available at much lower prices at various online retailers. International orders can also be placed on the producer’s site, but the consumers are responsible for checking their country’s legislation regarding the imports of mushroom based supplements (some countries may prohibit the import of such supplements).
The return policy is available only for damaged or defective products reported as such within 10 days from the day of receipt. In the case of returning a product for any other reason, a 4% restocking fee is charged to the client. No free sample seems to be available for this formula (or any of the products offered by this manufacturer for that matter).
7) Suggested Use
The suggested dose is 2 capsules daily with or without food, or as prescribed by the physician.
8) Our Bottom Line
Lion’s Mane is an herbal nutritional product offered as one of the many mushroom based products available from this producer. It is described as a high quality formulation obtained through s specific technological process that preserves the properties of the active substances. The product delivers an amount of 500 mg of Lion’s mane mycelium, which is the common dose of such supplements.
It is not possible to determine whether this dosage is effective or safe, as a daily recommended intake has not been established yet. Although the mushroom has been used for medical purposes for a long time, scientific evidence fails to provide conclusive and sufficient evidence about the effects of this supplement in humans. Preliminary research supports the neuroprotective benefits of Lion’s Mane extract.
Given the insufficient research and the fact that the product is not approved to treat, diagnose or cure any disease, it is best to consult a healthcare practitioner before using Lion’s Mane.Although it seems like making lifestyle changes can be hard, they don't have to be with the right clinically-proven supplement.
But how about our readers' pick for this year? There are lots of excellent brain supplements out there - right? When it comes down to high-quality and effectiveness, it's no surprise that our preferred product is HCF® Happy, Calm & Focused. Unlike far too many supplements, HCF proposes a unique FQ formulation that can do a lot in promoting optimal brain health.
|Similar Lion's Mane Related Proucts:||
10+ Yrs Proven
|HCF Happy, Calm & Focused
Frequently Asked Questions about Lion's Mane
Lion's Mane includes the following ingredients: Lion's Mane (Hericium erinaceus), freeze-dried myceliated brown rice, and Pullulan (an extra-cellular polysaccharide).
Lion's Mane is a dietary supplement promoted as a natural memory and nerve support. The formula is developed by the mycologist and author Paul Stamets and offered by the company Fungi Perfect. The formula is advertised as Certified Organic and contains 500 mg of freeze-dried Lion's Mane mycelium.
The active ingredient is a medicinal mushroom used for a long time as a treatment for disorders of the digestive system (like stomach and duodenal ulcers). The research involving this ingredient in the treatment of neurodegenerative disorders has shown promising results. Several clinical trials involving both humans and animal subjects have revealed the neuroprotective properties of Lion's mane active substances (Hericenones and Erinacines).
Lion's Mane reviews are generally positive and in a relatively high number. Testimonials from consumers are available on various online sites. Lion's Mane benefits are numerous, but there is still a lot of research needed to be done in order to determine all the risks and implications of such a treatment.
This is a dietary formulation based on a single active ingredient. The product is not unique, and it contains the usual amount of active substance used within this type of supplements (500 mg per serving). However, a daily value has not been established, so it is uncertain whether this amount is suitable for all categories of people.
The main disadvantage of this formulation is that it is expensive as compared to similar products, particularly if it is ordered online from the manufacturer's site. Various retailers offer this product at almost half the price (which is still higher than some products provided by competitors). The manufacturer's site offers little information about the specific benefits of their formula, but there is a lot of information available for online consulting on various other sites. Lion's Mane benefits target many other areas aside cognition and nerve cell health.