BrainReference is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.
We aim to provide consumers with helpful, in-depth information about brain health products. Whether we make money or not on a certain page does not influence the core mission of our writers and medical reviewers, which is to publish content that is accurate and informative.
All product names, logos, and brands are the property of their respective owners.
For more information, see our full Advertising Disclosure
Lion’s Mane Review – 12 Reasons To Consider
Lion’s Mane has confirmed itself as one of the leading supplements for supporting overall cognitive function. The supplement also claims to increase memory, support immunity, and enhance focus.
Our Lion’s Mane review below will analyze the most critical elements of this herbal supplement, starting with the manufacturer and finishing with the claimed benefits, cost per serving, potential side effects, and what real buyers think of the product.
1) Lion’s Mane Quick Facts
Lion’s Mane is advertised as a top nootropic brain and immunity booster that provides the highest possible dosage of Lion’s Mane available on the market. Dr. Emil’s formula is enhanced with BioPerine, a Black Pepper extract clinically claimed to aid in absorption.
It is one of the best-selling herbal supplements on Amazon, amassing over 13,000 positive reviews from genuine buyers. The product offers 2,100 mg of 100% organic Lion’s Mane extract sourced from farms from the United States, is non-GMO and gluten-free, and it doesn’t contain any harmful additives or fillers.
2) Who Makes Lion’s Mane
According to the official website, Dr. Emil Nutrition is a leading, growth health and wellness brand selling quality dietary supplements through its website and its leading presence on Amazon. This company’s popular products include Multi Collagen Plus, Bedtime Burn, 5-HTP Plus, EZ Doze, Fortis, Mana, CoQ10 Active, and Joint-X.
Dr. Emil Nutrition is a subsidiary of Brand Holdings, LLC, a business focused on acquiring and growing companies in the eCommerce space.
How to contact Dr. Emil Nutrition:
- Address: 3700 Butler St, Pittsburgh, PA 15201, USA
- Website: dremilnutrition.com
- Email: firstname.lastname@example.org
- Phone: 844-437-3645
3) What Are Lion’s Mane Ingredients?
Lion’s Mane contains the following active ingredients:
- Organic Lion’s Mane Mushroom powder 2.1 g
- Black Pepper fruit extract (BioPerine) 10 mg
Other inactive ingredients include magnesium stearate and hypromellose.
4) Does Lion’s Mane Work and it is Safe?
Lion’s Mane contains two active ingredients: a high dose of Lion’s Mane extract and a small amount of BioPerine (a patented extract of the Black Pepper fruit), which is added to improve absorption.
Lion’s Mane (Hericium erinaceus) is a type of medicinal mushroom long used in traditional Chinese medicine and widely available in supplement form.
While the mushroom has been used for centuries to treat a wide range of health concerns, research on Lion’s Mane’s specific benefits is relatively limited. However, conclusions from small clinical trials, test-tube studies, and animal-based research indicate that Lion’s Mane may offer several health benefits, including support for neuronal health.
The brain’s ability to form and grow new connections typically diminishes with age, which may explain why some cognitive functions get worse in many older adults.
Limited research suggests that Lion’s Mane may protect against dementia. Clinical studies revealed that Lion’s Mane mushrooms contain two unique compounds that can stimulate brain cells’ growth: hericenones and erinacines.
Furthermore, animal studies concluded that Lion’s Mane might help defend against Alzheimer’s disease, a degenerative brain disease that causes progressive memory loss.
For instance, Lion’s Mane mushroom and its extracts have proven to reduce symptoms of memory loss in mice, as well as limit neuronal damage generated by amyloid-beta plaques, which accumulate in the brain during Alzheimer’s disease.
According to a small study published in Biomedical Research in 2010, Lion’s Mane may help alleviate anxiety and depression. For the study, 30 menopausal women consumed cookies containing either a placebo or Lion’s Mane daily for one month.
Analyzing study findings, researchers noted that members of the Lion’s Mane group had less difficulty concentrating and were less irritable and anxious than the participants who received the placebo.
5) Lion’s Mane: Pros and Cons
Lion’s Mane claimed benefits include:
- Offers the highest concentration of Lion’s Mane available;
- Enhanced with BioPerine for improved absorption;
- Each capsule contains 100% pure Lion’s Mane extract powder from hand-picked, USA-grown mushrooms;
- Supports brain health;
- Immune support;
- Doctor formulated and backed by science.
6) Is Lion’s Mane Safe for Everyone?
This brain supplement contains Lion’s Mane mushroom, which is LIKELY safe when taken as recommended.
While more research is needed, no adverse effects have been seen in rats, even at doses as high as 2.3 grams per pound (5 grams per kg) of body weight per day for one month or lower dosages for three months.
Individuals with known allergies to mushrooms should avoid taking this supplement. There have been documented cases of people experiencing trouble breathing or skin rashes after exposure to Lion’s Mane mushrooms, likely related to allergies.
We recommend cycling the supplement regularly. The available research suggests that herbal extracts are more likely to cause adverse effects and negative interactions with specific prescriptions when continuously taken for more than 30 days.
We also recommend taking one week off every three weeks as a minimum. Longer breaks are advised after repeated cycles.
7) Lion’s Mane Warnings and Precautions
Lion’s Mane may slow blood clotting, increasing the chances of bruising and bleeding in people with bleeding conditions. Avoid taking Lion’s Mane if you are under treatment with medications that slow blood clotting (anticoagulant or antiplatelet meds).
Some medications used for diabetes include Glyburide (Glynase PresTab, DiaBeta, Micronase), Glimepiride (Amaryl), Insulin, Pioglitazone (Actos), Metformin (Glucophage), Rosiglitazone (Avandia), Glipizide (Glucotrol), Chlorpropamide (Diabinese), or Tolbutamide (Orinase).
8) Where to Purchase Lion’s Mane
You can purchase Lion’s Mane from the company’s official store or several online retailers such as Amazon, eBay, or Walmart.
9) Lion’s Mane Cost
One bottle of Lion’s Mane is priced at $22.50 (90 capsules / 30 servings).
10) Suggested Use
As a dietary supplement, take three (3) capsules once per day with at least 8 oz. of water or as directed by a healthcare professional.
11) What the Customer Lion’s Mane Reviews Say
"So the first day, I didn't feel anything, but just after the second day, it hit and every day after that (about eight days now). I have issues with energy and focus a lot at work due to a lot of analysis and writing, but I love the focus this pill gives me. It allows me to stay on track and accomplish what I need to, and I keep track of the other tasks and deadlines." [Read full review]
"The product has proven some benefits after continued seven-day use. At first, I took the three pills in the morning without food, but I would feel a little nauseous. But a little food would settle my stomach. The benefits of 7-day use include neurological crispness, intellectual fluidity, and mood enhancement. People like me now!" [Read full review]
"The first bottle I bought contained grey capsules. I never had Lion's Mane before, but they seemed to be effective. This product would be great if it were consistent, but I don't trust the manufacturer right now - no effects on the second batch and a waste of money." [Read full review]
---Paul M Crutchfield
12) Final Thoughts on Lion’s Mane
Lion’s Mane is one of the best-selling herbal brain supplements on Amazon. A significant role in this success is played by the company that has an excellent reputation among its customers and the straightforward formulation consisting of just two active ingredients.
Lion’s Mane has been shown to have a variety of health benefits – it may protect against dementia, reduce mild symptoms of depression and anxiety, and help repair nerve damage.
It also has potent anti-inflammatory, antioxidant and immune-boosting abilities and has been shown to lower the risk of heart disease, cancer, ulcers, and diabetes in animals.
Overall, Lion’s Mane is a high-quality herbal supplement that may be a good choice for those looking for an affordable supplement to improve focus, memory, and support the immune system.It's great that you're focusing in on brain health, take a look at supplements that support focus, there are quality products out there that won't break the bank.
An excellent calm, focus, and attention supplement in 2021 is HCF® Happy, Calm & Focused. Begining in 2001 and 45 countries worldwide, the company has been dedicated to only the foundational building blocks of life; amino acids, vitamins, and minerals, unlike the artificially stimulating/inhibiting herbal ingredients or the common high-dose 'all-in-one' products found on the market today for attention challenges. Uniquely formulated and using only clinically proven ingredients, HCF works to make your journey towards brain health one you can stick with for the long term.
|Lion's Mane Customers Related Products:||
10+ Yrs Proven
|HCF Happy, Calm & Focused
Customers Questions and Answers with Lion's Mane
Dr. Emil Nutrition Lion's Mane contains the following active ingredients: Organic Lion's Mane Mushroom powder and Black Pepper fruit extract (BioPerine).
Dr. Emil Nutrition Lion's Mane is a nootropic brain and immunity booster that claims to provide the highest possible dosage of Lion's Mane available on the market.
This brain supplement contains Lion's Mane mushroom, which is LIKELY safe when taken as recommended. Individuals with known allergies to mushrooms should avoid using the product as it may cause mild adverse effects such as skin rashes, headaches, and trouble breathing.
You can purchase Dr. Emil Nutrition Lion's Mane from the company's official store or several online retailers such as Amazon, eBay, or Walmart.
One bottle of Dr. Emil Nutrition Lion's Mane is priced at $22.50 (90 capsules / 30 servings).
Dr. Emil Nutrition Lion's Mane may improve memory, support the immune system, and enhance focus.
Dr. Emil Nutrition Lion's Mane is a best-selling herbal supplement on Amazon, and it's made by a reputable company known for producing quality supplements. The core ingredient - Lion's Mane extract - has been shown to have various health benefits. However, most of the research has been conducted on animals, and a lot more data is still needed before knowing if the mushroom has similar benefits in humans.
This nootropic supplement contains Lion's Mane that may interact with certain prescriptions. We strongly recommend consulting a medical doctor before taking the nootropic if you are under treatment or have known medical conditions.
You can take the nootropic with other dietary supplements or your daily multivitamin. However, we recommend consulting a healthcare provider before doing so.
Dr. Emil Nutrition Lion's Mane is not intended for children or teenagers under 18.
Dr. Emil Nutrition Lion's Mane contains 100% organic Lion's Mane extract and organic Black Pepper fruit extract. The product is also free of hormones, dairy, gluten, and GMOs.
Dr. Emil Nutrition Lion's Mane is intended for individuals looking for a natural alternative to improve focus, memory, and support the immune system.
Pregnant women should avoid using Lion's Mane products as insufficient evidence is available to determine if any dosage is safe during pregnancy.
As a dietary supplement, take three (3) capsules once per day with at least 8 oz. of water or as directed by a healthcare professional.
You can contact Dr. Emil Nutrition's customer support by email at email@example.com or phone at 844-437-3645.
All Dr. Emil Nutrition products sold on Amazon or its official website are accompanied by a full 60 days money-back guarantee. If you are not completely satisfied, simply write a brief explanation of your negative experience with the product to firstname.lastname@example.org and write "Refund Request" in the subject line.
Most buyers are happy with the Dr. Emil Nutrition Lion's Mane brain supplement. Still, some users complained about experiencing mild adverse effects (i.e., headaches) after taking the supplement.
Dr. Emil Nutrition Lion's Mane reviews and testimonials on Amazon are very positive. The supplement is rated 4.4 out of 5 (13,162 ratings), with 84% of the users rating the product with at least 4 stars.
Lion's Mane is made by Dr. Emil Nutrition.
- Dr. Emil Nutrition's official website. Retrieved on March 30, 2021.
- Shengjuan Jiang, Yuliang Wang, and Xiaolong Zhang - Comparative studies on extracts from by different polarity reagents to gain higher antioxidant activities. Retrieved on March 30, 2021.
- Vikineswary Sabaratnam, Wong Kah-Hui, Murali Naidu, and Pamela Rosie David - Neuronal Health – Can Culinary and Medicinal Mushrooms Help? Retrieved on March 30, 2021.
- Sara N. Burke and Carol A. Barnes - Neural plasticity in the aging brain. Retrieved on March 30, 2021.
- Puei-Lene Lai, Murali Naidu, Vikineswary Sabaratnam, Kah-Hui Wong, Rosie Pamela David, Umah Rani Kuppusamy, Noorlidah Abdullah, and Sri Nurestri A. Malek - Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Retrieved on March 30, 2021.
- Koichiro Mori, Yutaro Obara, Takahiro Moriya, Satoshi Inatomi, and Norimichi Nakahata - Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Retrieved on March 30, 2021.
- Tzeng Tsai-Teng, Chen Chin-Chu, Lee Li-Ya, Chen Wan-Ping, Lu Chung-Kuang, Shen Chien-Chang, Huang F. Chi-Ying, and Chen Chien-Chih, Young-Ji Shiao - Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice. Retrieved on March 30, 2021.
- Jurong Zhang, Shengshu An, Wenji Hu, Meiyu Teng, Xue Wang, Yidi Qu, Yang Liu, Ye Yuan, and Di Wang - The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model. Retrieved on March 30, 2021.
- Mayumi Nagano, Kuniyoshi Shimizu, Ryuichiro Kondo, Chickako Hayashi, Daigo Sato, Katsuyuki Kitagawa, and Koichiro Ohnuki - Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Retrieved on March 30, 2021.
- Hariprasath Lakshmanan, Jegadeesh Raman, Pamela David, Kah-Hui Wong, Murali Naidu, Vikineswary Sabaratnam - Haematological, biochemical and histopathological aspects of Hericium erinaceus ingestion in a rodent model: A sub-chronic toxicological assessment. Retrieved on March 30, 2021.
- Il-Dong Park, Hwa-Seung Yoo, Yeon-Weol Lee, Chang-Gue Son, Min Kwon, Ha-Jung Sung, Chong-Kwan Cho - Toxicological study on MUNOPHIL, water extract of Panax ginseng and Hericium erinaceum in rats. Retrieved on March 30, 2021.
- I-Chen Li, Yen-Lien Chen, Li-Ya Lee, Wan-Ping Chen, Yueh-Ting Tsai, Chin-Chu Chen, and Chin-Shuh Chen - Evaluation of the toxicological safety of erinacine A-enriched Hericium erinaceus in a 28-day oral feeding study in Sprague-Dawley rats. Retrieved on March 30, 2021.
- Munehide Nakatsugawa, Hiroki Takahashi, Chikako Takezawa, Kazutaka Nakajima, Kazutoki Harada, Yoshitaka Sugawara, Shuichi Kobayashi, Tatsuo Kondo, and Shosaku Abe - Hericium Erinaceus (yamabushitake) extract-induced acute respiratory distress syndrome monitored by serum surfactant proteins. Retrieved on March 30, 2021.
- M. F. Maes, H. M. van Baar, and C. J. van Ginkel - Occupational allergic contact dermatitis from the mushroom White Pom Pom (Hericium Erinaceus). Retrieved on March 30, 2021.
- Lion's Mane - examine.com. Retrieved on March 30, 2021.
- Hericium Erinaceus - rxlist.com Retrieved on March 30, 2021.
- Hericium Erinaceus - webmd.com. Retrieved on March 30, 2021.