BrainReference is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.
We aim to provide consumers with helpful, in-depth information about brain health products. Whether we make money or not on a certain page does not influence the core mission of our writers and medical reviewers, which is to publish content that is accurate and informative.
All product names, logos, and brands are the property of their respective owners.
For more information, see our full Advertising Disclosure
DLPA (DL-Phenylalanine) Review – 8 Things You Should Know
DLPA (DL-Phenylalanine) is a supplement with two versions of phenylalanine, an amino acid that’s important for maintaining a healthy lifestyle. DLPA promises to help with your nervous system, mood, endocrine system, and more. It’s put together by Carlson Laboratories, which was created more than fifty years ago in Chicago. Sometime after 1965 they expanded into the city suburbs, and have been there ever since. They offer more than 250 supplements for a variety of dietary needs, including vitamins and fish oils. Their entire process is transparent and well-documented.
1) What is DLPA (DL-Phenylalanine)?
Each capsule contains 500 mg of DL-phenylalanine, a combination of L-phenylalanine and D-phenylalanine. L-phenylalanine is an essential amino acid and generally considered the better half of this formula. It’s involved with norepinephrine, dopamine, and L-tyrosine, all the while easily penetrating the blood brain barrier. D-phenylalanine isn’t an essential amino acid and can help with alcohol withdrawal, arthritis, and Parkinson’s disease.
2) DLPA (DL-Phenylalanine) Ingredients
DLPA (DL-Phenylalanine) contains the following ingredients: DLPA (DL-Phenylalanine), Magnesium Stearate, Beef Gelatin Capsule
3) Does DLPA (DL-Phenylalanine) Work?
Each capsule contains 500 mg of DLPA inside of a gelatin capsule. There are no fillers or additives, just what’s supposed to be there. DLPA stands for DL-Phenylalanine, which is a mixture of D-phenylalanine and L-phenylalanine. Phenylalanine is found naturally in breast milk and in a variety of products, including supplements. It’s thought to have analgesic effects (pain relief) and antidepressant properties. You can also find it in foods like eggs, chicken, beef, spinach, and tofu.
L-phenylalanine is involved with the synthesis of norepinephrine and dopamine, can be converted into L-tyrosine, and passes the blood brain barrier more easily than D-phenylalanine. For skin diseases such as vitiligo, 50 to 100 mg of L-phenylalanine is used daily. It’s considered an essential amino acid.
Some research says that D-phenylalanine can help people cope with alcohol withdrawal, arthritis, and Parkinson’s disease. In some cases it’s better to take D-phenylalanine than DL-phenylalanine. And unlike L-phenylalanine, D-phenylalanine is not an essential amino acid.
In general, phenylalanine is not well studied. Doses and side effects vary between products, and can have dangerous interactions with some medications and conditions. Consult your doctor before buying DLPA, even though side effects almost never appear. Some people believe DL-phenylalanine is effective in treating pain, but there aren’t many studies which support this idea. Still, it can function as a placebo analgesic, while delivering other benefits to your brain.
4) DLPA (DL-Phenylalanine) Claims
- Phenylalanine is an essential amino acid that the human can’t effectively produce on its own, so a supplement may be helpful for some people. It’s found in a lot of foods but vegans don’t eat most of them.
- May improve your mood and cognitive function, and 500 mg is likely a good dose for this, as it’s well inside the safe zone. The most common serving size is between 100 and 500 mg daily, depending your needs.
5) DLPA (DL-Phenylalanine) Warnings and Precautions
- L-phenylalanine is found in commonly eaten foods so it’s unlikely people will need a supplement for it, a similar situation to Omega-6s. D-phenylalanine is made in laboratories and can have benefits, but it’s not usually considered as important as L-phenylalanine. In some studies, DL-phenylalanine was less effective than just L-phenylalanine or just D-phenylalanine.
- Some people want to use DLPA for treating pain, but there isn’t any good research to support the idea that DL-phenylalanine is effective in treating pain. It’s often considered no better than a placebo, which explains why some people think DLPA works for them.
6) How Much Does DLPA (DL-Phenylalanine) Cost?
Since each bottle contains 60 capsules and you’re supposed to take 1 every day, this is very inexpensive. It’s one of the cheapest supplements on the market and is easy to purchase. You can find Carlson products online and in local stores, so you have good chances at getting free shipping on your supplements.
7) DLPA (DL-Phenylalanine) Directions
One source noted that with amino acid supplements, it’s best to take them on an empty stomach with water or juice, an hour before your next meal. Certain high protein foods may interfere with the absorption of DL-phenylalanine, mostly because L-phenylalanine is found is many high protein foods. It’s in milk, eggs, chicken, beef, spinach, tofu, and more.
8) Our Verdict on DLPA (DL-Phenylalanine)
DLPA promises a lot but the effects aren’t too clear. There isn’t much research on the benefits and potential side effects of DL-Phenylalanine supplements. Some people might find this product useful, while others won’t see any upsides. It’s best to ask your doctor about DLPA before deciding to purchase it. If you do go ahead with DLPA, it’s very inexpensive and from a reputable company, so it’s likely that you’ll enjoy what DLPA has to offer. Some companies use DL-phenylalanine as part of an effective nootropic stack, although on its own your results may vary. Your mood may improve, but DL-phenylalanine might be most effective with other ingredients too.While there are some benefits, there are also alternatives to add to your existing brain supplementation plan, like a product with a proven track record.
HCF® Happy, Calm & Focused is Among the most acclaimed Amino Acids [Blend] products we've encoutered over the years. HCF unique FQ formula contains only high-quality nutraceutical-grade amino acids and associated neuro-nutrients scientifically proven to improve attention, focus, clairty, and support mood.
|DLPA (DL-Phenylalanine) Customers Also Bought:||
10+ Yrs Proven
|HCF Happy, Calm & Focused
Common DLPA (DL-Phenylalanine) Questions and Answers
DLPA (dl-phenylalanine) includes the following ingredients: DLPA (DL-Phenylalanine), Magnesium Stearate, Beef Gelatin Capsule
Mind-boosting supplements with amino acids are considered among the best, since amino acids can cross the blood brain barrier. DL-phenylalanine is especially effective in achieving this goal because of its neutral properties. Phenylalanine deficiency can lead to confusion, memory problems, and some symptoms of depression. It's important to have enough L-phenylalanine in your diet, as it can boost your mood and general cognitive function. DL-phenylalanine isn't studied in enough detail to know what it can really do for you, but some people swear by it. If your think DLPA is for you, it's very inexpensive and might do great things for you.