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CalmTrex Review – 8 Things You Should Consider
CalmTrex is presented as a cutting-edge nutritional formula that may be effective in assisting with common symptoms of depression, and anxiety, lowering stress, enhancing attention span and concentration skills, and generally improving cognitive function. This is one of the numerous products offered by the American manufacturer Stop Aging Now. Because they have been present on the healthcare products market for almost 2 decades, they have a very good reputation among consumers. They sell their nutritional supplements internationally through direct marketing, through retailers, or by direct distribution in healthcare stores and pharmacies.
CalmTrex is sold as a natural supplement that features 100% Zembrin, a patented extract of the Sceletium tortuosum plant, a natural anxyolitic and sedative remedy. This standardized compound is the most researched extract of this herb and was clinically shown to promote balanced mood, reduce anxiety, and improve alertness in the subjects involved.
The formula features two more active substances to potentiate the cognitive and mood balancing benefits. These are Vitamin B12 and lemon balm extract.
CalmTrex is addressed strictly to adults who are not currently under any other medication. The formula’s high quality is also guaranteed by the fact that it is processed in an DFA inspected facility to meet the rigorous USP standards.

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1) What is CalmTrex?
This nutritional supplement is based on a relatively low number of active compounds.
The main nutrient is Zembrin, a patented extract of the herb Sceletium Tortuosum, researched for its believed benefits on the nervous system and brain. This is advertised as a unique, rapidly acting botanical extract developed over 10 years ago and clinically researched ever since. The main benefits supported by scientific evidence are those on the cognitive flexibility and executive function. Researchers all over the world agreed upon the plant’s calming effects that are also non-habit forming and very well tolerated. More so, the plant has been used as a traditional remedy against depression and stress for hundreds of years, so its therapeutic effects are also empirically demonstrated.
Another active compound with mood balancing and cognitive benefits is the well-known Vitamin B12, included here in its most bio-available form, as Methylcobalamin. This nutrient has been shown to participate in numerous bodily processes that benefit different areas of the human body, the most important being the cardiovascular and the nervous systems. The connection between reduced levels of vitamin B12 and mood changes including anxiety and depression symptoms, and physical and mental fatigue has been observed in numerous clinical trials conducted so far. Side effects may include nausea, itching, blood clotting, or allergic reactions, particularly when very high amounts are ingested.
The suggested dose for CalmTrex is 1 vegetable capsule per day with a meal, or as directed.
2) Ingredients of CalmTrex
CalmTrex contains the following ingredients: Vitamin B12 (as methylcobalamin), Lemon balm extract (Melissa officinalis) (leaves) (Std. to 3% rosmarinic acid), Zembrin (Sceletium tortuosum) (herb), Microcrystalline cellulose, Hydroxypropyl methylcellulose (capsule), and vegetable Magnesium Stearate.
3) What Does CalmTrex Do?
Sceletium tortuosum has been traditionally used as a medicinal plant in South Africa. The main uses of this plant were to relieve fatigue, elevate mood, relieve thirst and hunger, and reduce depression and anxiety (as a sedative).
Zembrin is the main active compound featured in this supplement. This is a standardized herbal extract clinically researched for its effects on reducing stress and anxiety levels, alleviate depression symptoms, and promoting a general sense of wellbeing. Zembrin is believed to act in two different ways and result in PDE4 inhibition and 5-HT reuptake. The combination is in fact what makes this compound such a potent natural stress reliever. Existing clinical trials seem to support the compound’s action on the neural circuits involved in processing emotions, and particularly in managing anxiety feelings and stress. The scientific tests also seem to confirm the cognitive enhancing benefits of Zembrin. However, these trials are rather limited and reduced in size (up to 100 participants/study). One randomized, double-blind, placebo-controlled trial involving 37 participants has shown that Zembrin is a well-tolerated and safe, revealing no significant changes in the general health state of these subjects (vital signs, laboratory tests, ECG, etc.)
There are testimonials posted online about CalmTrex. What is being stated include:
This formula is amazing. I am an exhausted person, which has made me very, very irritable. My energy level hasn’t improved, but I am not nasty or irritable/ I was experiencing some feelings of anxiety, and this supplement relieved it in a short time. I would recommend it as it seemed to work for me. / Since I started using it, my hands used to perspire without any reason and that has stopped completely, I did not sleep well, and now I can have a good night rest, and finally I don’t experience side effects like I did with medication.
4) CalmTrex Benefits & Results
- The formula features all-natural scientifically proven active substances
- The formula comes with a 100% 365-day money-back guarantee
- The manufacturer enjoys a very good international reputation and has a vast experience in formulating nutritional supplements
5) CalmTrex Warnings and Precautions
- There is no clinical evidence of the formula’s potency
- There are no testimonials at the moment to support the product’s potency (other than the few found on the product’s page)
- There is no free sample offered for the formula.
6) CalmTrex Price
CalmTrex is sold in bottles of 30 veggie capsules that ensure the necessary supply for one month. The standard price is affordable and can be classified as a moderate one. Significant discounts are offered for clients who decide to join the Autoship Program, which means purchasing 3 or 6 bottles every 3-6 months. The formula can be delivered internationally by the manufacturer, but shipping taxes are rather high, depending on the country of delivery. US and Canada clients benefit of lower shipping charges and may choose between 2 shipping services (Ground or 2-Day Air). Like all Stop Aging Now’s supplements, the formula benefits of a 365 days refund.
7) Suggested Use
CalmTrex testimonials are available for online consulting both on the manufacturer’s site, and as well on the web pages of other retailers.
8) Final Thoughts on CalmTrex
CalmTrex formula is a trademarked form of Zembrin offered by Stop Aging Now and is marketed as a potent natural antidepressant suitable for those who seek a safer alternative to traditional medication.
The formula’s effectiveness is owed to the active compound shown in clinical trials to assist in the synthesis of an important neurotransmitter related to mood and behavior, called Serotonin. The effectiveness of this compound is however supported by a limited number and relatively reduced in size clinical trials. But still, this is an increasingly more popular nutrient which has gained a good reputation mostly because the plant has been used for decades for its soothing effects and has shown to be effective in reducing stress-related disorders.
The formula itself is not clinically tested, but there is a sufficiently large number of testimonials to help you get an idea about its potential side effects and actual benefits. Those who consider purchasing such a product are advised to consult a healthcare practitioner and make sure that it suits their individual needs.
Finding calmness is an integral part of a healthier lifestyle. To achieve this, focus on lifestyle changes like exercise and diet, and consider a supplement formulated specifically for calmness and focus.
HCF® Happy, Calm & Focused is Among the most acclaimed Amino Acids [Blend] products we've encoutered over the years. HCF unique FQ formula contains only high-quality nutraceutical-grade amino acids and associated neuro-nutrients scientifically proven to improve attention, focus, clairty, and support mood.
Furthermore, we love that they offer our readers access to a free sample for a limited time.
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Common CalmTrex Questions and Answers
- Recent:
CalmTrex includes the following ingredients: Vitamin B12 (as methylcobalamin), Lemon balm extract (Melissa officinalis) (leaves) (Std. to 3% rosmarinic acid), Zembrin (Sceletium tortuosum) (herb), Microcrystalline Cellulose, Hydroxypropyl Methylcellulose (capsule), and Vegetable Magnesium Stearate.
CalmTrex formula is advertised as a breakthrough formula with mood elevating benefits. The company that produces and markets this product is the American manufacturer Stop Aging Now.
The formula is a trademark of Zembrin, a patented botanical extract of Sceletium tortuosum. This is a plant that has been used traditionally for hundreds of hears as a natural remedy with calming effect believed to possess strong antidepressant and anxyolitic properties. Clinical trials involving this plant have particularly focused on this patented extract and revealed a clear link between its active chemicals the levels of stress and anxiety measured in the human subjects, particularly in reducing them.
CalmTrex reviews can be consulted online (available on various sources). CalmTrex ingredients also include Vitamin B12 and lemon balm to potentiate the mood balancing benefits of the formula.
CalmTrex is a nutritional formula advertised to feature 100% Zembrin, a patented standardized extract of the Sceletium tortuosum plant. This compound is most commonly used within scientific trials involving the plant and has been clinically shown to induce a sedative effect and reduce common anxiety and depression symptoms. This supplement is advertised to bring many other benefits including increasing attention, improving motivation, and enhancing concentration in a natural, side-effect free manner, unlike conventional antidepressants. However, the formula itself has not been clinically researched, so there is no evidence of its Effectiveness and safety. A daily recommended value for Sceletium tortuosum based formulations has not been established, and while it is considered safe for most people, there are some unwanted side effects to be careful at. These include headaches, poor appetite, depression, and even intoxication symptoms.
People already under medication are advised, as always, to avoid using such formulations without first informing their physician.
CalmTrex is one of the best natural antidepressants I have tried. After quitting prescription drugs (due to the numerous side effects I was experiencing) I tried different brands of herbal remedies and dietary supplements to alleviate my depression. And I stopped to this one because it is very effective in a small period of time. If I miss my daily dose I immediately feel sad and get annoyed very fast. CalmTrex has helped me to become a better person!
I like this herbal remedy because it works very fast and help me be less aggressive and feel happier. I have also noticed an improvement in my sleeping patterns lately.
I’ve only been taking it for 4 days and I feel great! I sleep great and have a sharper mind.
Are all the ingredients non-stop or organic? I am allergic to corn….and anything they make with corn. Thank you for taking time to answer.my question.
Nancy,
CalmTrex ingredients are not organic, and it contains milk (Ashwagandha is prepared following Ayurvedic tradition resulting in trace quantities of milk remaining in the product). However, it doesn’t contain any of the more common allergens like egg, fish, shellfish, tree nuts, wheat, soy, and peanuts.
How do I order Calm Trex, I have used it, and can not find a place to get replacements, would you please help me out.
CalmTrex is available online on Stop Aging Now official store. They even offer some deals: 1 bottle (one month supply) for $29.95, 3 bottles for $80.85, and 6 bottles for $149,70.