BrainReference is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.
We aim to provide consumers with helpful, in-depth information about brain health products. Whether we make money or not on a certain page does not influence the core mission of our writers and medical reviewers, which is to publish content that is accurate and informative.
All product names, logos, and brands are the property of their respective owners.
For more information, see our full Advertising Disclosure
Adderall Review – 15 Things To Consider
Adderall is a stimulant prescription medication that contains a mixture of four amphetamine salts: dextroamphetamine saccharate, dextroamphetamine sulfate, amphetamine aspartate monohydrate, and amphetamine sulfate.
Dextroamphetamine and amphetamine are central nervous system stimulants. They impact chemicals in nerves and in the brain that contribute to hyperactivity and impulse control. Adderall is generally prescribed to treat attention-deficit disorder (ADD), attention-deficit hyperactivity disorder (ADHD), and narcolepsy.
1) Quick Overview
Adderall is considered a first-choice treatment option for ADHD. Studies show that it improves attention, focus, and reduces impulsive behaviors. Between 75% and 80% of children with ADD/ADHD will see improved symptoms with the use of stimulant prescription drugs.
Adderall is also a valid option for increasing daytime wakefulness in individuals with narcolepsy, although there is little related research.
2) Who Makes Adderall
Adderall’s history starts with introducing a popular weight loss drug called Obetrol by the pharmaceutical company Rexar. In 1973, Rexar was forced to withdraw Obetrol from the market under the Kefauver Harris Amendment to the Federal Food, Drug, and Cosmetic Act due to the effects of the Drug Efficacy Study Implementation (DESI) program (which showed a lack of efficacy).
After making small adjustments to their original formulation, Rexar re-released Obetrol, despite lacking FDA approval. This slightly different formula was sold for several years.
After the acquisition of Rexar by Richwood Pharmaceuticals in 1994, Obetrol was marketed as a treatment for ADD, ADHD, and narcolepsy. After receiving numerous FDA citations for significant CGMP violations related to Obetrol, Richwood Pharmaceuticals rebranded their former weight-loss drug as the ADD/ADHD treatment Adderall we know today.
After the merge of Richwood Pharmaceuticals with Shire PLC in 1996, the newly emerged pharmaceutical company introduced the current Adderall brand as an instant-release tablet.
The first generic version of Adderall IR was released in 2002.
Shire Pharmaceuticals LLC contact information:
- Phone: +1 617 349 0200;
- Address: 300 Shire Way, Lexington, MA 02421, United States;
- Website: shire.com.
3) Ingredients of Adderall
Adderall contains the following active ingredients: dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfate.
Now, let’s take a closer look at the four amphetamine salts available in Adderall’s formula. Reviews of clinical stimulant research have confirmed the effectiveness and safety of long-term continuous amphetamine use for the treatment of ADHD.
The two reviews mentioned above have indicated that long-term continuous stimulant therapy for ADHD is effective for enhancing the quality of life and academic achievement, reducing the core symptoms of ADHD (i.e., impulsivity, inattention, and hyperactivity), and producing improvements in a large number of functional outcomes across nine categories of results related to antisocial behavior, academics, non-medicinal drug use, driving, obesity, self-esteem, occupation, social function, and service use (i.e., occupational, academic, financial, health, and legal services).
The Cochrane reviews on the treatment of ADD/ADHD in subjects of all ages with pharmaceutical amphetamines asserted that short-term studies have demonstrated that these drugs decrease the severity of symptoms. Still, they have higher discontinuation rates than non-stimulant medications due to their adverse side effects. A Cochrane review on the medication of ADD/ADHD in children with tic disorders such as Tourette syndrome showed that stimulants, in general, do not make tics worse. Nevertheless, large doses of dextroamphetamine could worsen spasms in some patients.
4) What Does Adderall Do?
Adderall is the brand name for prescription medicine that contains amphetamine and dextroamphetamine. It is available in two formulas: Adderall XR (extended-release) and Adderall IR (immediate-release).
Adderall XR formula works for ten (10) to twelve (12) hours. On the other hand, Adderall IR is short-acting and lasts for approximately four (4) hours.
Since Adderall is available in both extended and intermediate versions, it allows for better flexibility in how it can be prescribed. For example, a patient might be prescribed Adderall XR to take daily and have Adderall IR take when a more instantaneous effect is needed or when it is beneficial to have the medication wear off before bedtime.
5) What Adderall Does?
Some Adderall claimed benefits include:
- Increased focus;
- Less impulsivity;
- It raises dopamine and norepinephrine levels throughout your brain.
6) Side Effects of Using Adderall
- Weight loss
- Stomach ache
- Decreased appetite
- Dry mouth
- Trouble sleeping
- Loss of interest in sex
- Constipation or diarrhea
If more severe adverse effects develop, call a doctor right away. Serious side effects of Adderall may include:
- Irregular heartbeat
- Changes in vision
- Chest pain
- Aggressive behavior
- Uncontrollable behavior
- Trouble breathing
- Uncontrolled movements or voice sounds
- Severe weakness or numbness
- Swelling of face, lips, or tongue
- Difficulty swallowing or talking
- Hallucinations or delusions
- Severe skin rash
7) Adderall Product Warnings
Adderall is a powerful prescription drug that can interact with a wide range of other prescription drugs, over-the-counter medications (OTC), dietary supplements, herbs, or illegal drugs.
People undergoing treatment with monoamine oxidase inhibitors (MAOI) should not take Adderall. MAOIs include:
- Selegiline (Eldepryl, Emsam, Zelapar)
- Phenelzine (Nardil)
- Isocarboxazid (Marplan)
- Tranylcypromine (Parnate)
Types of drugs that are also known to interact with Adderall and may cause problems include:
- Blood pressure medications (adrenergic blocker or alpha-blockers), like Prazosin (Minipress), Doxazosin (Cardura), and Alfuzosin (Uroxatral);
- Blood thinners, like Warfarin (Coumadin);
- Seizure medications, like Phenytoin (Dilantin), Phenobarbital (Luminal, Solfoton), and Ethosuximide (Zarontin);
- Heart medications, like Metoprolol (Lopressor, Toprol XL), Labetalol (Normodyne), and Atenolol (Tenormin);
- Diuretics like Furosemide (Lasix);
- Prescription pain medications, including Propoxyphene (Darvon) and Meperidine (Demerol);
- Drugs used to treat bipolar disorder or schizophrenia, like Haloperidol (Haldol).
8) Is Adderall a Scam?
Several lawsuits have occurred in the past few years involving two of the most popular prescription drugs in the United States: Adderall and Ritalin. These lawsuits were initiated by plaintiffs who stated that they were injured by the dangerous adverse effects of Adderall and Ritalin or that the medical doctor encouraged the use of these drugs to help boost the manufacturers’ profits.
9) Who Sells Adderall?
Adderall is a prescription medication. That means it can’t, and it shouldn’t be bought from questionable sources. It is available, however, at most drugstores.
10) Adderall Price
Adderall (brand name) for a month’s supply, without insurance, can cost from around $140 to $420 depending on the frequency and dose. Adderall is also available in generic versions (a mixture of amphetamine salts), which can be considerably more affordable. However, some patients find that generic versions of Adderall are not as powerful for them as the brand version.
11) Other Similar Products
One of the most commonly asked questions is: “are there any alternatives to Adderall?” However, because Adderall is a prescription drug, we can only review prescription medicines as potential alternatives. We don’t advocate substituting a treatment directed by your physician with an over-the-counter dietary supplement.
Vyvanse is a brand name for a drug that contains lisdexamfetamine. When lisdexamfetamine enters the body, it is changed to dextroamphetamine. Vyvanse is available in one formula and is effective for approximately 14 hours.
The FDA approved this prescription drug in 2007 and is prescribed to treat people six years and older. In addition to treating ADD/ADHD, lisdexamfetamine can also be prescribed to treat binge eating disorder.
Concerta (Methylphenidate) is a controlled substance used to treat attention deficit hyperactivity disorder (ADHD). It works by activating the areas of your brain that are responsible for paying attention and staying focused.
Unlike Adderall, Concerta is only available as an extended-release tablet in various strengths: 18 mg, 27 mg, 36 mg, and 54 mg.
Dexedrine (Dextroamphetamine sulfate) is a prescription medication available in the form of fast-acting or long-acting capsules. Dexedrine is principally used to treat ADHD (attention deficit hyperactivity disorder) in children ages 3-12, adolescents, and adults. According to the FDA, Dexedrine is a federally controlled substance (CII) because it can be abused or lead to addiction.
12) Adderall Directions
Doses of Adderall are individualized, so your dosage will depend on why you’re taking Adderall, and on your response to the drug. Typically, physicians will prescribe a lower dose and increase the amount as needed.
In the case of children, the starting dose typically is 5 mg daily, and it can be increased gradually to 30 mg daily.
13) Of the Same Product Line
Adderall is available in several variations:
- Adderall IR – 5mg, 7.5mg, 10mg, 12.5mg, 15mg, 20mg, and 30mg
- Adderall XR – 5mg, 10mg, 15mg, 20mg, 25mg and 30mg
14) Adderall Reviews
"I am 30 years old and have ADHD. I have been taking Adderall for approximately three years now. The last dose (25 MG XR 24 hours as my doctor states) I received makes me extremely irritable, especially when my concentration gets broken." [Read full review]
"I've had only one side effect taking Adderall IR 20mg: dry mouth. I did get a slight headache at the end of the day when it started to taper off, but nothing bothered me. " [Read full review]
"I was diagnosed at 50 yrs old, and for most of the past 20 years, I have taken Dexedrine. For a year or so because I had a new doctor, I was prescribed Adderall and hated it. It made me jittery, and my focus and ability to concentrate for periods were awful." [Read full review]
"I have always struggled in school, and my parents did not believe in ADD or ADHD. I would listen to someone talk to me for 10 minutes and not tell you one word that they said. I went from a D student at a very good university to making the Dean's list." [Read full review]
Adderall is one of the most popular ADD/ADHD drugs available in the United States. However, based on your condition, Adderall may not be the correct treatment for you.
If you are wondering which ADD/ADHD medication is best for your child, consult with his pediatrician first. Finding the optimal medication often involves some back and forth with your physician as each individual responds differently to each prescription.
When you start taking a new medication, monitor how it makes you feel, including adverse effects. Then inform your doctor so they can make the necessary adjustments if needed.Adderall has proven beneficial for many, we also suggest taking a look at other supplements designed for your specific ailments.
HCF® Happy, Calm & Focused is one of the most praised Other [Blend] brain supplements we've come across after looking at thousands of 'calm and focused' supplements. Trusted for over 10 years with the highest quality, simple, and clean ingredients for effectively nourishing the brain, HCF Science has been dedicated to only the foundational building blocks of life; amino acids, minerals, and vitamins, unlike the common high-dose 'all-in-one' or artificially stimulating/inhibiting nootropics found on the market today for supporting calm and focus.
|Adderall Customers Also Purchased:||
10+ Yrs Proven
|HCF Happy, Calm & Focused
Customers Questions and Answers with Adderall
Adderall contains the following active ingredients: dextroamphetamine saccharate, dextroamphetamine sulfate, amphetamine aspartate monohydrate, and amphetamine sulfate.
Adderall is a prescription drug commonly used in the treatment of ADD/ADHD in children, adolescents, and adults.
Adderall can cause mild, moderate, and severe side effects, including dizziness, irregular heartbeat, restlessness, nausea, weight loss, dry mouth, headache, trouble sleeping, stomach ache, chest pain, decreased appetite, nervousness, loss of interest in sex, seizures, constipation, severe skin rash, diarrhea, changes in vision, aggressive behavior, uncontrollable behavior, trouble breathing, uncontrolled movements or voice sounds, severe weakness or numbness, fainting, difficulty swallowing or talking, hallucinations or delusions, and swelling of face, lips, or tongue.
As a prescription medication, Adderall is available for purchase at most pharmacies.
Adderall (brand name) for a month's supply, without insurance, can cost from around $140 to $420 depending on the frequency and dose.
Adderall contains two dextroamphetamine salts and two amphetamine salts. Dextroamphetamine salts and two amphetamine are central nervous system stimulants. These two substances work by regulating chemicals in the brain and in nerves that contribute to hyperactivity and impulse control.
Adderall was not designed to enhance brain functions but to regulate chemicals responsible for impulse control and hyperactivity.
Please note that many other prescription medications may affect the way Adderall works. The drug could also affect other medicines. It's imperative to let your physician know about everything you are taking before starting a treatment with this prescription drug. Potential dangerous interactions include any over-the-counter (OTC) medications, herbs, dietary supplements, and illegal drugs.
As with all prescription medication, we advise caution when taking Adderall with other prescription medication or over-the-counter dietary supplements. Drugs that may interact with Adderall include Prazosin (Minipress), Doxazosin (Cardura), Alfuzosin (Uroxatral), Warfarin (Coumadin), Phenytoin (Dilantin), Phenobarbital (Luminal, Solfoton), Ethosuximide (Zarontin), Metoprolol (Lopressor, Toprol XL), Labetalol (Normodyne), Atenolol (Tenormin), Furosemide (Lasix), Propoxyphene (Darvon), Meperidine (Demerol), and Haloperidol (Haldol).
Adderall can be used in the treatment of ADD/ADHD in children ages 6 to 12, adolescents, and adults.
Adderall contains a mixture of four amphetamine salts. These chemical substances have been studied across multiple clinical trials and shown to cause mild, moderate, and even severe side effects in some patients.
You should not be taking Adderall unless it was prescribed to you by a physician.
All prescription drugs used to treat ADD/ADHD - including Ritalin, Adderall, and Vyvanse - are in the FDA's Class C, which means they are not definitely safe during pregnancy, and they are not definitely harmful.
You may take Adderall with or without meals, first thing in the morning. Any supplementary doses should be spread out and taken every four to six hours. Try not to take Adderall tablets later in the evening unless recommended by your medical doctor.
You can contact the Shire Pharmaceuticals LLC customer support department by phone at +1 617 349 0200, by mail at 300 Shire Way, Lexington, MA 02421, United States, or by using the Contact Us form available on their official website.
As Adderall is a prescription medication, please discuss any possible returns or refunds with the doctor who prescribed it.
Most complaints gravitate around Adderall's many adverse effects, the many drug negative interactions, and its habit-forming properties.
Adderall reviews are mixed. While this prescription drug may be efficient in some people, there are also many cases in which Adderall was inefficient.
Adderall is produced and marketed by U.S.-based Shire Pharmaceuticals LLC.
- dailymed.nlm.nih.gov. Adderall XR- dextroamphetamine sulfate, dextroamphetamine saccharate, amphetamine sulfate and amphetamine aspartate capsule, extended-release. Retrieved on February 10, 2020.
- Leslie Briars and Timothy Todd - A Review of Pharmacological Management of Attention-Deficit/Hyperactivity Disorder. Published in June 2016.
- web.archive.org. National Drug Code Directory. Retrieved on February 10, 2020.
- accessdata.fda.gov. Center for Drug Evaluation and Research. Approval Letter Application Number 11522, S010. Retrieved on February 10, 2020.
- Shire Pharmaceuticals LLC official website. Retrieved on February 10, 2020.
- link.springer.com. Yu-Shu Huang and Ming-Horng Tsai - Long-Term Outcomes with Medications for Attention-Deficit Hyperactivity Disorder. Published in July 2011.
- ncbi.nlm.nih.gov. L. Eugene Arnold, Paul Hodgkins, Hervé Caci, Jennifer Kahle, and Susan Young - Effect of Treatment Modality on Long-Term Outcomes in Attention-Deficit/Hyperactivity Disorder: A Systematic Review. Published online on February 25, 2015.
- ncbi.nlm.nih.gov. Xavier Castells, Lídia Blanco‐Silvente, and Ruth Cunill - Amphetamines for attention deficit hyperactivity disorder (ADHD) in adults. Published online on August 9, 2018.
- cochranelibrary.com. Salima Punja, Larissa Shamseer, Lisa Hartling, Liana Urichuk, Ben Vandermeer, Jane Nikles, and Sunita Vohra - Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents. Published online on February 4, 2016.
- ncbi.nlm.nih.gov. Sydney T. Osland, Thomas D.L. Steeves, and Tamara Pringsheim - Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders. Published online on June 26, 2018.
- americanaddictioncenters.org. Amanda Lautieri - Long-Term Effects of Adderall Use. Retrieved on February 11, 2020.
- healthline.com. Ann Pietrangelo and Kristeen Cherney - Effects of Adderall on the Body. Retrieved on February 11, 2020.
- rxlist.com. Adderall. Retrieved on February 11, 2020.
- hg.org. Adderall Lawsuits. Retrieved on February 11, 2020.
- addictionresource.com. Adderall Class Action Lawsuit Settlements and Legal Actions. Retrieved on February 11, 2020.
- ncbi.nlm.nih.gov. Wholesale Prices of Prescription ADHD Medicines. Retrieved on February 11, 2020.
- vyvanse.com. Official Vyvanse website. Retrieved on February 11, 2020.
- accessdata.fda.gov. Drug Approval Package. Retrieved on February 11, 2020.
- ncbi.nlm.nih.gov. David W. Goodman - Lisdexamfetamine Dimesylate (Vyvanse), A Prodrug Stimulant for Attention-Deficit/Hyperactivity Disorder. Published in May 2010.
- ncbi.nlm.nih.gov. Vishal Madaan, Venkata Kolli, Durga P Bestha, and Manan J Shah - Update on optimal use of lisdexamfetamine in the treatment of ADHD. Published online on July 22, 2013.
- additudemag.com. Concerta: ADHD Medication Overview. Retrieved on February 11, 2020.
- accessdata.fda.gov. Dexedrine. Retrieved on February 11, 2020.