UPDATED 05/02/2016

Zyprexa Review
Zyprexa Review

PUBLISHED: 03/08/2012 by BR Technical
Editor's Review: 2.2/5.0
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Zyprexa is the trade name for Olanzapine and isproduced by Eli Lilly Pharmaceutical, a U.S. based company with over 130 years of market experience. According to the manufacturer, the product is recommended in the treatment of manic or mixed episodes associated with bipolar I disorder and in the treatment of schizophrenia.

Zyprexa’s anti-psychotic properties and efficiency have been tested, as the manufacturer claims, through several clinical trials. A long list of side-effects is known to be associated with the product. Special precautions refer to administrating the drug to adolescents, diabetes patients and elderly people.

The drug contains Olanzapine, an atypical anti-psychotic which affects various neurotransmitters in the brain, particularly serotonin (5HT) and dopamine. These 2 neurotransmitters are responsible for regulating mood and behavior.

This is an FDA approved prescription drug and should be taken after a complete medical evaluation has been performed.

Zyprexa Ingredients

Zyprexa contains the following active ingredient: Olanzapine.
Inactive ingredients: carnauba wax, crospovidone, microcrystalline cellulose, hydroxypropyl cellulose, hypromellose, lactose, magnesium stearate, and other inactive ingredients.

Product Features

The drug has been successfully used in the treatment of schizophrenia and bipolar disorder. The producer mentions several clinical test being conducted on schizophrenia and bipolar disorder patients, for two age groups: adults (over 17 years old) and adolescents (13-17 years old). Safety and effectiveness of the drug have not been established for children under the age of 13.

Therefore, for pediatric patients the medication should be prescribed only after a thorough diagnostic evaluation and with careful consideration to the potential risks. Pregnant and nursing women are advised not to use the product unless the product benefits justify the high potential risk incurred by the fetus.

A wide range of side effects have been associated to Zyprexa. Most common refer to hyperlipidemia, weight gain, seizures, mouth dryness, constipation, increased appetite, dizziness, fatigue and cognitive and motor impairment.

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  • Good manufacturer reputation
  • Successfully used as a treatment for schizophrenia and bipolar disorder
  • FDA approved
  • Clear use directions
  • Clinically tested.


  • Long list of potential harmful side-effects
  • Rather high price.


Zyprexa is currently one of the most popular antipsychotic prescription drugs in the world. The manufacturer, Eli Lilly Pharmaceuticals, has a yearly sales income of approximately 3 billion dollars from Zyprexa sales exclusively.

The drug’s efficacy principle is simple: Olanzapine, the active ingredient, corrects imbalances of certain neurotransmitters in the brain, imbalances which lead to manic depression and schizophrenia.

There are many side-effects and precautions associated with the product. Health condition, current medication, the severity of the condition being treated, age and other factors influence the recommended daily dosage, therefore a prior treatment medical evaluation is mandatory.

The product is rather expensive, but doctors may offer free samples before starting actual treatment.

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Zyprexa ReviewBR Technical2.252016-05-02 12:09:31
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