UPDATED 05/17/2016

OPC Synergy Review
OPC Synergy Review

PUBLISHED: 10/30/2012 by BR Publishing
Editor's Review: 3.3/5.0
Product Star Rating 10yrs or More
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OPC Synergy

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OPC Synergy is a dietary supplement advertised to provide a synergistic blend of antioxidants designed to support cell functioning. The formula is offered by Standard Process, an experienced manufacturer of dietary supplements, which claims the product’s core benefits include support for the normal cell functioning, eye health, cardiovascular system and the complex processes associated with aging.

Standard Process is a U.S. based company founded more than 80 years ago. The company manufactures and markets over 300 products including veterinary formulas, whole food supplements, and herbal supplements. According to the company, the entire range of products is compliant to the Good Manufacturing Practice (GMP) requirements set forth by the Food and Drug Administration.

The formula contains Oligomeric Proanthocyanidins, one of the most powerful antioxidant known today. OPC Synergy is designed for adults only.

OPC Synergy Ingredients

OPC Synergy includes the following ingredients: Grape (Seed) Extract (Masquelier’s Original OPC Included), Red Wine Extract (Provinols), Green Tea (Leaves) Extract (60% Catechins), Bilberry (Fruit) (25% Anthocyanins), Proprietary Blend: Dried buckwheat (leaf) and juice, green tea (leaf) powder, and dried carrot (root), gelatin, water, Calcium Stearate, and colors.

Product Features

OPC Synergy features extracts of plants and seeds with powerful antioxidant properties. The Grape Seed Extract featured by the formula is claimed to contain OPC, a group of substances considered one of the most potent free radical scavengers ever discovered. Extensively researched, the nutrient is now officially recognized as “Vitamin P.” OPCs, commonly derived from a combination of red wine extract grape seed extract, and/or pine bark extract, have been scientifically demonstrated to be 20 times more effective than Vitamin C and 50 times more effective than Vitamin E as a free radical scavenger. OPCs are shown to cross the blood-brain barrier and improve oxygenation of brain tissue.

They are currently researched for potential benefits in Attention Deficit Hyperactivity Disorder and Attention Deficit Disorder. Several studies in animals show OPCs may improve memory associated to age-related cognitive decline. Animals receiving OPCs for five weeks showed improved spatial and object recognition. Clinical testing and scientific research in humans reveal no evidence for allergic reactions, toxicity, or carcinogenicity. OPC is 100% bioavailable in humans, being able to remain in the body for up to 72 hours.

Green Tea extract has a wide spectrum of medical applications. It contains coffee (2 to 4%), antioxidants and polyphenols. The extract is believed to assist with conditions ranging from Chronic Fatigue Syndrome and Parkinson’s disease to blood pressure and certain types of cancer. Polyphenols in its composition helps with Dopamine synthesis, an important neurotransmitter which regulates mood, motivation, decision making and attention. Green tea is considered generally safe, it may however cause stomach upset and constipation and in rare cases liver problems.

The daily serving is 1 capsule. The number of consumer reviews is extremely limited. No side effects or special precautions are mentioned for OPC Synergy.

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  • OPCs are strong antioxidants with researched and scientifically proven benefits
  • The product is available since the year 2000
  • The formula uses five different sources of OPCs ensuring a high quality of the nutrients


  • Moderate price (approximately $25 for a month’s supply)
  • Limited number of consumer reviews
  • Green tea contains coffee and may potentially be dangerous in high doses


OPCs have been discovered several decades ago in the 1950’s and have been investigated ever since research for its numerous potential benefits. They are known to be potent free radical scavengers, collagen binders and inhibitory of histamine formation and inflammatory enzymes to name its most important functions.

OPC Synergy has been manufactured for more than 10 years. Although the number of consumer reviews is extremely limited, we may assume the formula will achieve its benefits if we look at the manufacturer’s excellent reputation and the long availability of the product on the market. Potential side effects are associated to some of the ingredients. For cautionary reasons we recommend you talk to a healthcare provider before using OPC Synergy.

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OPC Synergy ReviewBR Publishing3.252016-05-17 12:09:31
OPC Synergy Review
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