UPDATED 05/23/2016

Natrol 5-HTP Mood Enhancer Review
Natrol 5-HTP Mood Enhancer Review

PUBLISHED: 03/21/2013 by BR Moderator
Editor's Review: 3.5/5.0
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Natrol 5-HTP Mood Enhancer is a drug free dietary supplement designed to promote a state of positive mood and to assist with appetite management. The formula manufactured by the popular company Natrol is based on the benefits of the plant-derived amino-acid 5-HTP. This amino acid has been thoroughly studied and proven to help balance levels of the neurotransmitter Serotonin, which plays a key role in regulating mood and in controlling appetite. This is why the product is advertised to help maintain a balanced, positively oriented mood while also supporting their diet goals.

Natrol is a U.S based company with a market experience of more than 30 years. Natrol is dedicated to developing nutritional supplements that meet the needs of their customers, products which embody the principles of both quality and innovation. The company goes to great lengths to ensure the quality of their products, undergoing numerous quality assurance and control tests.

Natrol 5-HTP Mood Enhancer should be used by healthy adults over the age of 18. Pregnant and lactating women should avoid use however. The manufacturer also warns that people who use prescription drugs, depression medicine, or medicines that aim to treat migraines, Parkinson’s, and psychiatric disorders should consult a healthcare professional prior to use.

Natrol 5-HTP Mood Enhancer Ingredients

Natrol 5-HTP Mood Enhancer contains the following ingredients: 5-HTP (5-Hydroxytryptophan) 100 mg (from Griffonia simplicifolia Seed), gelatin, water, rice, flour, magnesium stearate, and silica.

Product Features

Natrol 5-HTP Mood Enhancer contains a substance called 5-hydroxytryptophan, or 5-HTP. This is a naturally derived substance obtained from the seeds of a West African medicinal herb called Griffonia simplicifolia. In essence, 5-HTP is a derivative of the amino-acid called Tryptophan. In humans, this substance plays a role as a chemical precursor in the secretion process of Serotonin and Melatonin. These are important brain neuro-transmitters with a vast array of roles and applications.

Serotonin is one of the most important neurotransmitters, with essential roles in regulating mood, balancing emotion and behavior, promoting healthy sleep patterns, and regulating appetite. Recent discoveries suggest that it may play a role in the mechanism of depression and in decision making processes. Serotonin production declines with age, causing insomnia, anxiety, and depressed mood.

5-HTP prevents Serotonin depletion and intervenes in various forms of depression, insomnia and other sleep problems and some anxiety forms. Results of research conducted so far have been inconclusive or insufficient, hence further investigation is needed.

5-HTP supplements may potentially cause EMS, a disease which affects the muscles causing pain. This mainly occurs due to a contaminant known as Peak X sometimes found in Tryptophan and 5-HTP products, hence you must make sure that your supplement is pure and free of Peak X. Rare Natrol 5-HTP Mood Enhancer side effects include nausea. There are numerous consumer testimonials posted online. Consumers report satisfactory levels of effectiveness with a variety of symptoms associated to mood.

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  • Large number of consumer reviews
  • Drug-free formula
  • The manufacturer is a reputable company, a guarantee to the formula’s superior quality
  • Affordable price (approximately $20 for a month’s supply)


  • The benefits of 5-HTP still have to be supported by scientific evidence
  • Potential drug interactions
  • Not suited for pregnant and nursing women, and people under the age of 18


Natrol 5-HTP Mood Enhancer features as core ingredient the amino-acid derived 5-HTP, an ingredient which has stirred numerous controversies. Although it appears that 5-HTP stimulates serotonin production, and hence stimulates mood and suppresses appetite, the whole spectrum of side effects and interactions is not know. The fact that there were several cases of EMS, a severe muscle condition, caused by 5-HTP supplements has largely contributed to its negative image proliferation. The product itself has received numerous positive reviews, though and appears to be effective. You should however consult a healthcare provider, just to be on the safe side of things.

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Natrol 5-HTP Mood Enhancer ReviewBR Moderator3.52016-05-23 12:09:31
Natrol 5-HTP Mood Enhancer Review
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