UPDATED 05/01/2016

Marplan Review
Marplan Review

PUBLISHED: 04/30/2012 by BR Moderator
Editor's Review: 2.6/5.0
Product Star Rating 10yrs or More
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Marplan is a prescription drug used for treatment-resistant forms of depression. It is developed and distributed by Validus Pharmaceuticals, a US based pharmaceutical company with a focus on the neurological market. Their three main products are Marplan, Equetro and Rocaltrol, all of which are aimed at neurological or psychiatric conditions.

It is your doctor’s decision whether Marplan is the right treatment for you. If you have unsuccessfully tried several treatment forms for depression or anxiety, there is a possibility that Marplan will do the trick, but consumption of this product has been known to incur some risks. This is why it is very important to follow the indications on the prescription, to minimize the risk of negative effects taking place.

Marplan Ingredients

Marplan contains: isocarboxazid, lactose, corn starch, povidone, D&C Red No. 27, FD&C Yellow No. 3, and magnesium stearate.

Product Features

Marplan is one of few monoamine oxidase inhibitors still in clinical use, seeing as this class of medication is associated with a wide series of side effects. Like the rest of the drugs belonging to this class, it is normally prescribed in the cases in which conventional forms of medication have failed.

The mental disorders that this drug has been proven effective against are depression, social anxiety and panic disorder. It is also a possible treatment in case of Parkinson’s disease and other illnesses that incur dementia or depersonalization disorder, but the effects in these cases are not entirely certified.

As mentioned before, there is a large number of side effects associated with this medication, among which headaches, chest pain, weight gain, fainting, dizziness and tremors. It also has a lot of negative interactions with foods that contain tyramine, leading to the need of a carefully supervised diet while on this medication.

The dosage of Marplan is to be decided by the doctor prescribing it; as for the patient, it is very important that he or she respects all the indication provided with the medication, as consequences of not respecting the dosages or the diet can be dire.

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  • effective form of medication against a number of mental disorders
  • costs often covered by health insurance
  • dosage and administration methods already settled by doctor in almost all cases


  • large list of side effects
  • consumption of medication requires a strict diet to prevent negative effects
  • product belongs to a class known to cause addiction


Marplan is a very effective drug and most of the people it was prescribed to claim that it helped them fight the disorders from which they suffer. The major drawback is that it requires constant supervision and care; an unsupervised diet or dosage can lead to lethal side effects.

If you were prescribed Marplan by your doctor, it is essential that you respect the indications that were provided. As with all prescription medication, do not alter the dosages or allow anyone else to use your medication. If you’re currently taking any supplements or are using treatment for any other conditions, inform your doctor, as Marplan might have negative interactions with these.

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Marplan ReviewBR Moderator2.52016-05-01 12:09:31
Marplan Review
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