UPDATED 05/13/2016

Azilect Review
Azilect Review

PUBLISHED: 01/27/2014 by brreader
Editor's Review: 3.2/5.0
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Azilect is a prescription drug described as a treatment for many of the symptoms associated with Parkinson’s disease (PD). The formula is developed by Teva Pharmaceuticals Industries, a company that offers several categories of products targeted for different types of disorders. Their line of products comprises various products aimed to help people suffering from cancer, respiratory conditions, or special products designed to promote women’s health. The company leads an international business and prides with being one of the most popular producer of healthcare products.

Azilect drug is advertised as particularly beneficial for maintaining adequate amounts of Dopamine in the brain. This is an important neurotransmitter that plays several important roles in humans, including in movement coordination, memory, behavior, cognition, learning capacity, attention and mood. This drug is advertised as a way to maintain normal mobility in people who suffer from this neurodegenerative disorder, a common consequence of developing such a disease. Mobility impairment may manifest in the as slowness, tremor, stiffness, and/or trouble walking.

Azilect is specially designed for adults and can be administered as initial monotherapy or as adjunct therapy to levodopa (a common medication in Parkinson’s disease). It can be used as a stand-alone treatment (in early Parkinson’s disease) or with other medication when the disease is more advanced. The product is classified as a MAO-B inhibitor enhancing Dopamine levels.

Azilect Ingredients

Azilect contains the following ingredients: Rasagiline, Mannitol, starch, pregelatinized starch, Colloidal Silicon Dioxide, Stearic Acid, and talc.

Product Features

Azilect is the brand name under which the single active ingredient called Rasagiline is marketed. An Azilect generic product seems to have been approved by the FDA, while other brands also commercialize products based on this chemical.
This compound is an irreversible monoamine oxidase type-B inhibitor (MAO-B). It is a common treatment prescribed for Parkinson’s disease. This condition is a chronic and progressive disorder known to be caused by reduced Dopamine levels in the brain. Rasagiline is also researched as a treatment for another neurodegenerative disorder called Alzheimer’s disease. The main advertised benefits of this inhibitor target enhancing memory, including in people who suffer from age-related memory decline, enhancing mood and increasing learning ability. Some of the most significant and severe symptoms of the disease involve incontrolable movement. These symptoms may manifest as shakiness, slowness, stiffness and even difficulty in walking. Azilect (Rasagiline) is capable to inhibit the action of the MAO-B enzyme which is responsible for the breaking down of Dopamine. This way, the neurotransmitter is able to enter the BBB (blood-brain barrier) and to accomplish its many important roles including in maintaining proper coordination and mobility.

One of Azilect’s most concerning side effects refers to it potentially increasing the risk of skin cancer, particularly in patients with Parkinson’s. However, this concern has not been supported by clinical evidence and the FDA approved this medication in the treatment of this disease. Other Azilect side effects mentioned by the manufacturer include flu syndrome, joint pain, indigestion, and depression. As an adjunct therapy, the drug may lead to dyskinesia, weight loss, vomiting, nausea, constipation, and others (all mentioned on the official page). The Azilect drug interactions include other MAOIs, meperidine, tramadol, methadone, propoxyphene or St. John’s wort.

People who suffer from moderate to severe liver disease should not use this medication.
The suggested doe is 1 pill once daily, with or without food.

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Advantages

  • Azilect is an approved prescription drug in the treatment of Parkinson’s disease symptoms
  • The formula has been clinically studied
  • Available research indicates that the medication is effective in reducing the severity of Parkinson’s disease symptoms
  • Azilect reviews from consumers are generally positive
  • A detailed description of the product is offered by the manufacturer (the product benefits of a dedicated web-page that includes indications about the safety and proper usage of the formula)

Disadvantages

  • The medication is listed with a large number of drug interference and side effects, hence Azilect interactions and other use associated risks should previously be discussed with a healthcare provider
  • The product cannot be purchased without a prescription
  • Azilect side effects may manifest if taken alone or in combination with other drugs
  • No money-back guarantee is available

Conclusion

The Azilect drug is designed as a support in the treatment of a common degenerative disorder affecting elder individuals called Parkinson’s disease. The product is advertised to be helpful in relieving the symptoms involving mobility in these patients. This is one of the most common symptoms associated with the condition.
A study involving this drug has shown that the product is effective in increasing the available synaptic Dopamine with no significant adverse reactions as compared to placebo drugs. However, there are other clinical studies that failed to show such promising results. Based on these trials, some researchers have issued the statement that further research is needed before drawing a medical-evidence consolidated conclusion.

In any case, the main aspect to be kept in mind is that this product may become very dangerous if combined with other drugs or if it is used by certain categories of people. For complete information about the safety of this medication it is imperative to consult a healthcare practitioner.

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Azilect Reviewbrreader3.252016-05-13 12:09:31
Azilect Review
4.50 out of 5 based on 2 user ratings
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1 User Reviews about Azilect
  1. 1

    Michael Manson

    Azilect, in my opinion, is a terrible drug and almost killed me.
    The adverse reactions manifested over 18 months then exponentially
    increased when prescribed carb/levo but that was after starting. The 2014 added warnings were exactly
    what I was suffering but no one notified me of the changes and I was too incapacitated to respond though I informed my doctor every 60 days. Since going off I am recovering.